Found 89 matching trials
Trastuzumab and Letrozole in Treating Postmenopausal Women With Progressive Advanced Breast Cancer
PHASE2RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor grow...
Location
Kantonspital Aarau
A Study of T-DXd as Monotherapy or in Combination With Anti-cancer Agents in Patients With Selected HER2-expressing Tumors
PHASE2This is an open-label, multicenter, Phase II study to evaluate the efficacy...
Status
Active Not Recruiting
SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study
PHASE2This is a prospective, multicenter, open-label, randomized, controlled Stud...
Location
Multiple Locations
ELVN-002 in HER2 Mutant Non-Small Cell Lung Cancer
PHASE1The goal of this clinical trial is to test ELVN-002 in people with cancers ...
Status
Active Not Recruiting
Location
University of Colorado - Anschutz Medical Campus - PPDS
Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)
PHASE2DESTINY-Gastric03 will investigate the safety, tolerability, pharmacokineti...
Status
Active Not Recruiting
DESTINY-PANTUMOUR04
N/AThis study will evaluate the effectiveness of T-DXd in patients with HER2-p...
SMMART Adaptive Clinical Treatment (ACT) Trial
EARLY_PHASE1SMMART-ACT is a feasibility pilot study to determine if testing samples fro...
Location
Multiple Locations
FT536 Monotherapy and in Combination With Monoclonal Antibodies in Advanced Solid Tumors
PHASE1This is a Phase 1 dose-finding study of FT536 given in combination with a m...
Location
Honor Health Research Institute
Phase I/II Study of Intrathecal/Ommaya T-DXd in HER2-Expressing Breast Cancer With Leptomeningeal/Brain Metastases
PHASE1Multiple trials confirm systemic T-DXd efficacy in HER2+ breast cancer with...
Location
Fudan University Shanghai Cancer Center
89Zr-Trastuzumab PET/CT in Subjects With Previously Treated HER2-Positive Solid Tumors Scheduled to Receive Treatment With MT-5111
PHASE2This is an open-label, single center, pilot study to assess the feasibility...
Location
Multiple Locations